A new study for mothers having trouble sleeping | Vitae + Clara Health
Clara Health

If you are a mother who wishes she were more well-rested for her family, our study could help to provide relief.

Women in all types of families are more likely than men to wake up not feeling well-rested. That's why we're developing sleep treatment specifically for women.

No matter the family type, women report more sleeping difficulty than men. But most sleep treatments were developed and tested for and with men. So, at Vitae, we're developing a treatment designed, first and foremost, for women.

If you or a loved one are a woman between 18 and 64 who have had trouble sleeping - but haven't yet been diagnosed with a specific sleep disorder - you could qualify for free treatment through our research study.

difficulty sleeping

Sleeping difficulty is when you have trouble sleeping at night, and is very common in the US. It may be hard for you to fall asleep, or you may wake up several times throughout the night.

Zolpidem (Ambien) is often the first therapy prescribed to treat sleep difficulties in patients, but the clinical studies evaluating Ambien were done mostly on men. We want to change that.

What's the goal of this study?

During the course of this study, we will be providing women who have difficulty sleeping with low doses of a medication called Zolpidem (also called Ambien), which is FDA approved for treating difficulty sleeping.

The study aims to show that women who receive low doses of the medication do not suffer from the common side effects of the dosage that is currently given to women today, such as:

  • Morning drowsiness
  • Persistent sleepiness
  • Difficulty with tasks requiring coordination (such as driving a car).

Although it is currently possible to receive low doses of Zolpidem, it is often too expensive for many women to do so. We are providing this treatment to participants for free for the duration of the study, and up to two weeks after its completion.

Is this study right for me?

Who is this study for?

This study is accepting women who:

  • Are between the ages of 18-65
  • Do not have some specific sleep disorders, such as sleep apnea
  • Are not currently pregnant


What should I expect?

On the first day of the study, participants will take one tablet of Ambien, and have a conversation the next day with a trained Research Associate. If you felt like you slept well, you will continue to take one tablet per day. If not, then the next day you will take two tablets of the Ambien. Until you feel well rested, the amount of Ambien taken per night will gradually increase up to the standard dose that is given to women today (5mg).

Participating in this study involves:

  • Filling out a sleep diary, where you will record the times, amount, and quality of sleep you have.
  • Depending on the dosage of Ambien you need to feel well rested, you will participate in the study between 8 - 17 days.
  • Participants will receive $30 and a parking voucher for each visit. After the final visit, they will receive another $20 gift card.

After the study is complete, if you and your doctor agree that you should continue on the dose of Ambien that you felt was best, you will be provided the dose for free for an additional two weeks.


Frequently asked questions

Who is sponsoring the study?

Vitae is a life science company whose research is conducted together with the Brown University Medical School.

Where is the study being offered?

Providence, Rhode Island.

Mothers deserve treatments personalized for them.

Learn more about participating by filling out the contact form, or contacting Rachel Schneider by email at rachel_schneider@brown.edu or calling 508-505-6214.